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Through the medium of gene editing, a group of US scientists have made a breakthrough which would see the end of hereditary disease. Actual whoa.
Good news, everyone! Those heinous hereditary diseases that flay us (and those shiftless layabouts we produce to replace us) will soon be a thing of the past. The minds of science have been able to correct disease-causing gene mutation in human embryos, which would theoretically stop diseases passed to the next generation.
The new technique uses the gene-editing tool CRISPR to target a mutation in nuclear DNA that causes hypertrophic cardiomyopathy, a common genetic heart disease that can cause sudden cardiac death and heart failure. The research, published in the journal Nature, demonstrates the first time scientists have successfully tested the method on donated clinical-quality human eggs.
The author of the study, Shoukhrat Mitalipov, summed up the findings thusly: “…every generation on would carry this repair because we’ve removed the disease-causing gene variant from that family’s lineage…by using this technique, it’s possible to reduce the burden of this heritable disease on the family and eventually the human population.”
The collective stunned Keanu whoa you felt is accurate, because it’s rather a big deal.
Very simply, researchers worked with healthy donated human ovum and sperm carrying the genetic mutation, the equation being: Take embryos, add CRISPR and the mutant cells be gone. The new method is illustrated below:
— nature (@nature) August 2, 2017
The list of hereditary diseases that could be solved as a result of this breakthrough is staggering. Cystic fibrosis, haemophilia, sickle cell anemia, you will not be missed.